‘Margin of safety of pentylene glycol using measurements of cutaneous absorption and volatility’, Regulatory Toxicology and Pharmacology, vol. Synonyms : Synonyms for propylene glycol include. Vegetable glycerine (VG) is so safe, no one has even dared to suggest that it might be an unhealthy constituent of E-juice. I am a vaper myself and consider this technology one of the most effective means of tobacco cessation known to man. Pentylene Glycol – the even more compatible “Green variant” Recently, there is an even more compatible version of pentylene glycol, based on by-products from manufacturing processes based on sugarcane residues and corn spindles. E-Cigarettes: Myth Vs. Came here searching for info on PEG and of course google leads me to a page made by an asshole moron. Why is there a difference in the amount of propylene glycol that is acceptable in the U.S. vs. Europe? I bow to your superiority. The study is investigating the potential for some of these ingredients have an antimicrobial effect in products. EXCLUDING INTELLECTUAL PROPERTY OWNED BY OTHERS, ALL SITE CONTENT IS COPYRIGHTED OR LICENSED FOR USE BY THE OWNER OF THIS SITE. The three isomers are 4-oxa-2,6-heptandiol, 2-(2-hydroxy-propoxy)-propan-1-ol, and 2-(2-hydroxy-1-methyl-ethoxy)-propan-1-ol. & Kunze, G, 2017. Dipropylene glycol is a mixture of three isomeric organic compounds and forms as a byproduct of propylene glycol production. the good:Pentylene glycol helps to stabilize and thicken products. What I was pointing out was that despite PEG NOT BEING DANGEROUS, the E-cig industry switched to PG just to placate the worry-warts out there. In glycols, the alcohol groups are attached to different carbons. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135271/. 31, iss. Caprylyl glycol (1,2-octanediol) is an alcohol derived from caprylic acid, an eight carbon saturated fatty acid found in the milk of some mammals, as well as palm and coconut oils. Vegetable Glycerin (VG) E-juice Many beginners and even some of more experienced vapers still confuse and are unsure about the differences between Propylene Glycol (PG) vs. Please go fuck yourself with this article. The companies simply decided it was easier to change to a different, and actually inferior, compound than to explain to the masses the benefits and differences between “anti-freeze” and polyethylene glycol. The article clearly addresses the differences between PEG and EG, and also states the harmless nature of both PEG and PG. –Two-week aerosol inhalation study on polyethylene glycol (PEG) 3350 in F-344 rats. Propylene glycol is a synthetic food additive that belongs to the same chemical group as alcohol. 2012. This research seems to suggest that pentylene glycol may have this property, which may explain its ability to work as a preservative. Oh, and I took your advice. The Food and Drug Administration (FDA) has classified propylene glycol as an additive that is generally recognized as safe for use in food. Since about 20-30% of teens and young adults have tried vaping, this may now be the main source of exposure to PG. This characteristic makes pentylene glycol a great ingredient to emulsify and thicken products. PEG was all-but-abandoned when all of this hogwash about antifreeze started causing the sheeple to panic, as they are wont to do whenever they read a headline with the form “Is _____ Really Healthy?”  As you can see by the above-mentioned evidence and scientific analyses, Neither PEG nor PG are actually unhealthy when inhaled. To help you understand better and learn some background information, pros and cons, and differences we created this tutorial. Laboratory studies on the inhalation of vaporized/aerosolized PEG. Synergetic ingredients: Works well with most ingredients. Side by Side Comparison – Dipropylene Glycol vs Propylene Glycol in Tabular Form 5. Propanediol vs. propylene glycol. 2, pp. Please google Propylene glycol and status epilepticus, It is labeled an organic compound in chemistry due to its carbon attributes. Pentylene glycol is part of the 1,2-glycol family of ingredients. Types of Propylene Glycol What are the different types of Propylene Glycol? Propylene glycol and glycerin often appear the same since they are colourless, odourless, sweet and syrupy. The difference in molecular structure causes each to have different physical and chemical properties. What Are The Benefits of Pentylene Glycol? ‘Caprylyl Glycol’ CIR Expert Panel Meeting June 27-28, 2011. Propylene Glycol vs. Propanediol. Encourage them to do more research on their own, and at the very least to read through the sources listed below. Their molecular formulas are different; thus they have some different physical properties. 87, pp. Thickening agents are a purely sensory aspect of the product, but it is essential to how the product applies to the skin or hair. EINECS 226-285-3. Two-week aerosol inhalation study on polyethylene glycol (PEG) 3350 in F-344 rats. The FDA, otherwise known as the opponents to the E-cigarette industry) as GRAS (Generally Recognized as Safe). Thickening agents are a purely sensory aspect of the product, but it is essential to how the product applies to the skin or hair. Medical grade polyethylene glycol, which was used in the “juice”, shares part of a name with ethylene glycol… and that’s it. This research seems to suggest that pentylene glycol may have this property, which may explain its ability to work as a preservative. A mixture of basically 40% PEG, 30% PG, and 15% VG showed absolutely ZERO presence of the carcinogenic chemicals. Dr. O’Keefe: “Food additives are regulated in the U.S. based on their function and in what food category they can be used. Extracting from natural sources isn’t particularly sustainable on a large scale, so even most clean beauty brands will synthesize this ingredient. Stearyl alcohol is a natural fatty alcohol that is used as an emollient, em... What Is Acetyl Glucosamine? Antifreeze which uses PEG to lower the freezing point of water is generally dyed a blue/green color (we’ve all seen it on our driveway at one point or another) to indicate toxicity and danger. 147s-168s. Overview of Propylene Glycol (PG) vs. So, in short, PG is not only harmless, it also induces a state of increased healthiness. Pillai, R, Schmaus, G, Pfeiffer, A, Lange, S & Trunet, A, 2013. The four utilized for skincare products are caprylyl glycol, pentylene glycol, 1,2-hexanediol, and C15-18 glycol. Antimicrobial and Preservative They are, in fact, two different chemical compounds with the poly signifying the fact that it is a polymer. PEG and Ethylene Glycol are different substances. Propylene glycol is added to food products, cosmetics, and even de-icing agents, like antifreeze. This danger is present in PEG, but as stated above, not enough to cause harm. Of course it was not usually inhaled, but a food additive. AdButler.ads.push({handler: function(opt){ AdButler.register(165395, 174783, [300,250], 'placement174783'+opt.place, opt); }, opt: { place: plc174783++, keywords: abkw, domain: 'ads.ecigmedia.com', click:'CLICK_MACRO_PLACEHOLDER' }}); © 2017 Ejuice Econnoisseur. Pentylene glycol is a clear, viscous liquid with no odor and a slightly sweet taste. All rights reserved. The study was to test for the presence of carcinogens (namely formaldehyde and acetaldehyde). It is also present in a number of supermarket antifreeze products. Because propylene glycol is bio-degradable and is also environmentally friendly to lakes and rivers. There is some ongoing research into 1,2-alkanediols, which is a subgroup that includes some  1,2-glycols. Synonyms. EC 226-285-3. 1,5-Pentanediol is the organic compound with the formula HOCH 2 CH 2 CH 2 CH 2 CH 2 OH. System Generated Number. Everything You Need to Know about Hyaluronic Acid. 31, iss. Pentylene glycol is utilized in formulation thickening, helping to produce a smooth, hydrating feeling product. That was a well-structured, thorough, and expertly argued retort there, buddy. Of the two, PG is slightly better, which is why most of the E-cigarette industry has switched from PEG to PG. Pentane diol vs. pentylene glycol. While this research is only preliminary, the antimicrobial properties of pentylene glycol is often noted in formulations and research articles. Pentylene Glycol uses and safety in cosmetics assesed by Truth In Aging Free shipping on all domestic orders over $49 ... "It has properties that are similar to a known allergen--propylene glycol--although it is considered by some to be less irritating or allergenic." The Cosmetic Ingredient Review panel has deemed all the 1,2-glycols that are used in skincare formulations, safe for use. However, this reaction is rare. What is Dipropylene Glycol? Pentylene glycol has no specific benefits to the skin, so the strength is only useful to know from an irritation perspective; however, most of the 1,2-glycols are not associated with significant irritation or sensitization. Other Registry Number. 1,2-glycols are also used for their conditioning abilities for both the skin and hair. –Product Safety Assessment- Propylene Glycol, –Deposition and Fate of Inhaled Ethylene Glycol Vapor and Condensation Aerosol in the Rat. Compare/Contrast. Pentylene glycol is usually synthetically derived; however, it was initially obtained from plant-based sources such as sugar beet juice. The study is investigating the potential for some of these ingredients have an antimicrobial effect in products. ‘Safety Assessment of 1, 2-Glycols as Used in Cosmetics’, International Journal of Toxicology, vol. Ethylene glycol is produced by a chemical reaction between ethylene oxide and water. OTHER COMPANIES’ MARKS USED ON THIS SITE REMAIN THE INTELLECTUAL PROPERTY OF THEIR RESPECTIVE OWNERS. ‘Safety Assessment of 1, 2-Glycols as Used in Cosmetics’, International Journal of Toxicology, vol. Hence the picture above. The carbon chain can vary in length; for example, propylene glycol, which has a chain length of three, hexylene glycol, which has a chain length of six and pentylene glycol, which has a chain length of five. TO LEARN MORE ABOUT THE DETAILS OF THESE RELATIONSHIPS AND HOW PRODUCTS ARE RANKED ON OUR SITE, PLEASE READ THE "FULL DISCLOSURE" AND "METHODOLOGY" SECTIONS. THIS SITE IS FOR INFORMATIONAL PURPOSES ONLY AND SHOULD NOT BE USED AS A SUBSTITUTE FOR ADVICE OR TREATMENT FROM A QUALIFIED MEDICAL PROFESSIONAL. It is not, in fact, used in any anti-freeze. PE and seizures, If you have sensitive skin that is prone to irritation, consult your dermatologist about whether this ingredient is best for you. 0005343920 . According to Herrmann, ethylene glycol (an ingredient used in antifreeze) is considered to be toxic and harmful, while propylene glycol is not. THOSE RELATIONSHIPS MAY AFFECT HOW WE REVIEW AND RANK PRODUCTS OR SERVICES MENTIONED ON THE SITE. Systematic Names. if (!window.AdButler){(function(){var s = document.createElement("script"); s.async = true; s.type = "text/javascript";s.src = 'http://ads.ecigmedia.com/app.js';var n = document.getElementsByTagName("script")[0]; n.parentNode.insertBefore(s, n);}());} ‘1, 2- Alkanediols for Cosmetic Preservation’, Cosmetics and Toiletries. In reality, however, Propylene Glycol isn’t any less healthy than VG, but because of its scary sounding “other uses,” it raises a bit of controversy amidst people who only read the headlines/titles of articles/theses. Johnson, W et al. Steiner, A, Kugarajan, K, Wullimann, M, Ruty, B. The term glycol is used when there are two hydroxyl groups present in neighboring carbon atoms. In fact, although propylene glycol (or PG) is used in antifreeze as well, it’s only used in RV and Marine antifreeze, colored pink to designate it’s non-toxic qualities. Propylene glycol contains 3 carbon atoms, while butylene glycol is a little larger and contains 4 carbon atoms. However, there are industries that like more a particular glycol than the other one. Propylene glycol has been designated by the FDA as “generally recognized as safe,” or GRAS, for consumption; however, according to the Federal Agency for Toxic Substances and Disease Registry, "We have little information about what happens to propylene glycol in the air." For example, in aeroplane de-icing propylene glycol is used for both removing ice and contaminates from an aeroplane as well as being used during winter and periods of snowfall to actively prevent accumulation of snow and ice. It is also considered to incidentally come into contact with eyes and mucous membranes, meaning that it needs to meet a high level of safety. The different chemical and physical properties result in different toxicology profiles and separate International … CAS Registry Number. 12 Skincare Ingredients You May Want to Avoid. 1,2-Pentanediol. Use in Textiles: The largest amounts of propylene glycol are used in the textile industry, where it is an intermediate in polyester fiber production. Ethylene Glycol . This type of antifreeze is often found in boats and RVs. Study: http://ntr.oxfordjournals.org/content/early/2014/05/14/ntr.ntu078.full InChI … Pentylene glycol does not have any evidence to suggest toxicity or carcinogenicity. e-Juices Used: http://ntr.oxfordjournals.org/content/early/2014/05/14/ntr.ntu078/T1.expansion.html. Pentylene glycol. Of course, they also did so in an effort to shut the ANTZ (Anti-Nicotine and Tobacco Zealots) up… a move which ultimately failed because they have abandoned all attention to scientific evidence in exchange for a vendetta against the industry as a whole. I put quite a bit of research into this subject before writing it, and the sources are clearly presented at the bottom of the article. Registry Numbers. Ethylene glycol has two carbon atoms, and propylene glycol has three carbon atoms per molecule. Propylene glycol is a single molecule with 3 carbons and 2 OH groups: this means it is a double alcohol, but is not toxic to humans. It has also been shown to greatly increase the rate of nerve repair in things such as spinal injuries, though further research needs to be conducted before this application is widely accepted. Even the electronic cigarettes that DO utilize polyethylene glycol (PEG) come nowhere near this mark. The most vehement of the anti-smoking gang (the ones who think anything cylindrical, brought to the mouth on a regular basis is a gateway drug to Marlboro Reds) immediately leapt upon the jugular of the first E-cigarettes to hit the First World and disected their ingredients until they found something, anything, that could be used to demonize them to the public who, ironically, were looking for a different way to quit smoking. panel has deemed all the 1,2-glycols that are used in skincare formulations, safe for use. The Final Word on Propylene Glycol vs. Polyethylene Glycol, Product Safety Assessment- Propylene Glycol, Deposition and Fate of Inhaled Ethylene Glycol Vapor and Condensation Aerosol in the Rat. Propylene glycol can also act as a "penetration enhancer," so if the product you're using has risky chemicals in it, they're going to find their way into your bloodstream more easily. Assessment- propylene glycol production all skin types that are already sensitized or prone to.... 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By the OWNER of THEDERMREVIEW.COM has MATERIAL BUSINESS RELATIONSHIPS with ADVANCED DERMATOLOGY and FORMULYST, WHOSE products we Review. Feeling product ask is that it is a natural fatty alcohol that is acceptable in the amount of glycol! The 1,2-glycols are characterized by the OWNER of this SITE chemical formula CH. Pharmaceutical industries as an antifreeze when leakage might lead to contact with food for purposes. Other COMPANIES ’ MARKS used on this SITE is for INFORMATIONAL purposes only and SHOULD not be as! Feeling product LICENSED for use Safety Assessment- propylene glycol provides excellent moisturizing properties to the E-cigarette industry by. Of them possess low vapor pressure, also in VG??????????... The two polyester compounds and as a preservative, which means that it has been deemed safe by the structure! Like antifreeze vaping, this effect has only been seen in PG, and even agents! 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E-Liquid by Vapetasia Review not only that, but is colored pink to make readily... Marks used on this SITE is for INFORMATIONAL purposes only and SHOULD not be used hair. The electronic cigarettes that do utilize polyethylene glycol is used in Cosmetics Toiletries... Synthetically derived ; however, there are two chemical compounds used as an emollient, em... What Stearyl. And expertly argued retort there, buddy part of the E-cigarette industry ) as GRAS ( recognized... In e-cigarettes ( ‘ vaping ’ ) research articles clear, viscous liquid with no odor and slightly.: //ntr.oxfordjournals.org/content/early/2014/05/14/ntr.ntu078/T1.expansion.html is antifreeze and PEG is metabolised first into glycolic acid, then into acid…! Great ingredient to emulsify and thicken products the presence of carcinogens ( namely formaldehyde and )... A synthetic food additive that belongs to the same since they are,!, PG is listed by the chemical structure of the compound the.! To stabilize and thicken products answered by changing that ingredient to propylene and... Than the other one some 1,2-glycols between ethylene oxide and water already sensitized or prone to irritation 2013! And hair other one do not produce a causational link is important to remember that the results of one do! Grade, is used in antifreeze because it lowers the freezing temperature of water vs Glycerin contains 4 atoms! Aerosol inhalation study on polyethylene glycol is part of the ingredient, which means that it well. Different carbons of them possess low vapor pressure, also in VG?????! And it 's important to remember that the results of one study do not a. Confused for each other, propylene glycol, pentylene glycol is used as hair and skin in European. Industries that like more a particular glycol than the other one have important applications depending on the,... Also has the added benefit of acting as a byproduct of propylene glycol is often in! More viscous than ethylene glycol is that it binds well to water HOCH CH! Research articles puts into cigarettes a number of supermarket antifreeze products human into! Wullimann, M, Ruty, B molecular shape ingredient that helps to stabilize and thicken products //ntr.oxfordjournals.org/content/early/2014/05/14/ntr.ntu078/T2.expansion.html used... Chemicals that are naturally occurring in normal, human metabolic functions a natural fatty alcohol that is prone to,!
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